
Statistics show that approximately 4.6 million people living in the UK are diagnosed with diabetes. Individuals who are overweight or obese are seeking alternatives such as weight loss treatments and injections, which can help them reduce weight fast. However, among the weight loss injections, Wegovy (Semaglutide) and Mounjaro (Tirzepatide) have become people’s hope due to their results. Both have shown positive results, with Wegovy users losing an average of 15% of body weight compared to the placebo group, who lost only 2.4% in the 68 weeks. Mounjaro users have shown much more significant weight loss by losing 22.5% of their body weight over 72 weeks.
The main reason Mounjaro has demonstrated better results is dual-action, making it a better contender for weight loss treatment. Although these are defining results, without the consultation of a specialist, there are severe Mounjaro side effects that can lead to long-term consequences. Regular supervision and medical checkups are necessary to avoid these consequences. Wegovy side effects are also severe; therefore, it is essential to understand that specialist consultation is needed as it can lead to severe challenges in the long term.
By consulting with the doctor, individuals can better understand how these injections work and react with their body, and there are different doses of these injections. Moreover, other factors are also involved in a positive result, such as lifestyle management, diet changes, and exercising for a better period. However, before we understand the side effects of Wegovy and Mounjaro, let’s discuss how these work:

Mechanism of Wegovy in the Body
Wegovy (Semaglutide) works by acting on the brain parts responsible for regulating appetite. Copying the gut hormone GLP-1 suppresses appetite, which makes the individual feel fulfilled by easing food speed from the stomach to the intestine. The feeling of fullness leads to eating fewer calories, leading to weight loss over time.
Mechanism of Mounjaro in the Body
Mounjaro (Tirzepatide) works by activating the two receptors, GLP-1 and GIP. Similarly to Wegovy, it copies the GIP hormone, which triggers the signal through the brain. It helps the brain regulate energy balance by slowing down the digestive process, which regulates metabolism. Ultimately, it improves blood sugar control and releases insulin, which reduces glucose production. Unlike Wegovy, Mounjaro acts as a dual action, acting on two receptors instead of one.
Wegovy | Mounjaro |
Common Side Effects | |
One of the most common side effects prevalent in Wegovy users is nausea, mainly due to reduced appetite. Therefore, it is recommended to consult a doctor before increasing the dose. Other side effects include vomiting, which occurs due to severe nausea. Users have also reported constipation and diarrhoea. Moreover, stomach pain also occurs in Wegovy users. | Minor issues such as nausea, vomiting, and diarrhoea are similar to the Wegovy side effects. Other complications, such as constipation, moderate stomach pain and loss of appetite, occur. Bloating, indigestion, and inflammation have also been observed in the users. |
Major Health Risks | |
Other severe Wegovy side effects include users developing gallstones, which can lead to pain and require medical attention if it occurs. Kidney problems can also happen; although rare, increased heart rate is also seen in individuals. Low blood sugar can happen for those taking diabetic medications alongside Wegovy. | Pancreatitis inflammation is a complication that can arise through the use of Mounjaro. Moreover, gastrointestinal issues can lead to stomach bloating. However, dehydration can also occur through vomiting and diarrhoea, leading to kidney problems. Similar to Wegovy, low blood sugar can occur, leading to dizziness and sweating. |
What Do Doctors Recommend?
Doctors recommend reducing calorie deficits, working out, exercising, and getting check-ups for effective weight management. Other aspects, such as smaller meals, can help in the intake of weight loss injections. By reducing the diet, a person can manage nausea or vomiting.
Final Thoughts
In recent years, treatments, such as weight loss injections and medications, have increased. However, it is concerning that the percentage of overweight and obese people has been growing globally and not just in the UK. The reason behind the increase is the availability of processed and artificial foods, which have led to people consuming such items. Many health-related issues are caused by such food. Individuals who have gained a significant amount of weight are now resorting to weight loss injections and treatment to manage their weight. Although both Mounjaro and Wegovy have gained approval for distribution and have shown benefits, they should not be taken without professional medical advice as they can create issues that can be severe in the long term. Moreover, the dose should be increased gradually for individuals with previous medical problems to have a better effect. Understanding the mechanism of Wegovy and Mounjaro, how it works, and its side effects can help you choose the better alternative for your weight loss journey.